Ergin Kocyildirim, MD







McGowan Institute for Regenerative Medicine 3025 East Carson Street Suite 232 Pittsburgh, PA 15203


Research Assistant Professor 
Department of Cardiothoracic Surgery

Education and Training

Ankara University School of Medicine
University College London, Institutes of Child Health
Great Ormond Street Hospital for Children NHS Trust

Professional Activities

American Thoracic Society
European Association for Cardio-Thoracic Surgery
Turkish Cardiovascular Surgery Society

Journal Reviewing and Editorial Boards

Editorial Board, American Society of Artificial Internal Organs Journal
Editorial Board, Anatolian Cardiology Journal

Research Interests

Research interests include:

  • Functionally single ventricle
  • Failing Fontan
  • Ventricular Assist Devices
  • ECMO
  • Heart-Lung Transplantation
  • EECP
  • Stem Cell
  • Tracheal Stenosis
  • Acute Lung Injury
  • Intraoperative Imaging

Read more about Dr. Kocyilidirum's research at the McGowan Institute for Regenerative Medicine.


  1. Rojas M, Cárdenes N, Kocyildirim E, Tedrow JR, Cáceres E, Deans R, Ting A, Bermúdez C. Human adult bone marrow-derived stem cells decrease severity of lipopolysaccharide-induced acute respiratory distress syndrome in sheep. Stem Cell Res Ther. 2014 Mar 26;5(2):42. doi: 10.1186/scrt430. PubMed PMID: 24670268;  PubMed Central PMCID: PMC4055116.
  2. Shankarraman V, Kocyildirim E, Olia SE, Kameneva MV, Dzadony RJ, Maul TM, Simon MA, Champion HC, Wagner WR, Bermudez CA. Biocompatibility Assessment of the Levitronix® Centrimag® Adult ECMO Circuit in a Model of Acute Pulmonary Hypertension. ASAIO J. 2014 Mar 20. [Epub ahead of print] PubMed PMID: 24658516.   
  3. Murthi GV, Kocyildirim E, Sellathury S, Cuckow PM, Wilcox DT, Michalski A, Sebire NJ, Elliott MJ, Duffy PG. Wilms' tumour with persistent intravascular extension: a review of the surgical aspects of management. J Pediatr Urol. 2006 Oct;2(5):439-45.
  4. Johnson CA Jr, Wearden PD, Kocyildirim E, Maul TM, Woolley JR, Ye SH, Strickler EM, Borovetz HS, Wagner WR. Platelet activation in ovines undergoing sham surgery or implant of the second generation PediaFlow pediatric ventricular  assist device. Artif Organs. 2011 Jun;35(6):602-13. doi: 10.1111/j.1525-1594.2010.01124.x. Epub 2011 Apr 5. PubMed PMID: 21463346; PubMed  Central PMCID: PMC3178345.   
  5. Johnson CA Jr, Shankarraman V, Wearden PD, Kocyildirim E, Maul TM, Marks JD, Richardson JS, Gellman BN, Borovetz HS, Dasse KA, Wagner WR. Platelet activation  after implantation of the Levitronix PediVAS in the ovine model. ASAIO J. 2011 Nov-Dec;57(6):516-21. doi: 10.1097/MAT.0b013e31822e2535. PubMed PMID: 21989419. 
  6. Koçyıldırım E, Dur O, Soran O, Tüzün E, Miller MW, Housler GJ, Wearden PD, Fossum TW, Morell VO, Pekkan K. Pulsatile venous waveform quality in Fontan circulation-clinical implications, venous assists options and the future. Anadolu Kardiyol Derg. 2012 Aug;12(5):420-6. doi: 10.5152/akd.2012.126. Epub 2012 May 16. PubMed PMID: 22591937.  
  7. Maul TM, Kocyildirim E, Johnson CA Jr, Daly AR, Olia SE, Woolley JR, Snyder S, Bengston SG, Kameneva MV, Antaki JF, Wagner WR, Borovetz HS, Wearden PD; The Pediaflow Consortium. In Vitro and In Vivo Performance Evaluation of the Second Developmental Version of the PediaFlow Pediatric Ventricular Assist Device. Cardiovasc Eng Technol. 2011 Dec;2(4):253-262. PubMed PMID: 22211150; PubMed Central PMCID: PMC3247142.  
  8. Maul TM, Kocyildirim E, Marks JD, Bengston SG, Olia SE, Callahan PM, Kameneva  MV, Franklin S, Borovetz HS, Dasse KA, Wearden PD. Pre-clinical Implants of the Levitronix PediVAS(®) Pediatric Ventricular Assist Device - Strategy for Regulatory Approval. Cardiovasc Eng Technol. 2011 Dec 1;2(4):263-275. Epub 2011 Oct 27. PubMed PMID: 23494160; PubMed Central PMCID: PMC3594505.  
  9. Dur O, Kocyildirim E, Soran O, Wearden PD, Morell VO, DeGroff CG, Pekkan K. Pulsatile venous waveform quality affects the conduit performance in functional and "failing" Fontan circulations. Cardiol Young. 2012 Jun;22(3):251-62. doi: 10.1017/S1047951111001491. Epub 2011 Oct 19. PubMed PMID: 22008697.   
  10. Koçyildirim E, Ozkan S, Karadağ D, Köse SK, Ekici E, Ikizler C. Discrete supravalvular aortic stenosis in children: Is it necessary to reconstruct the whole aortic root? Anadolu Kardiyol Derg. 2009 Aug;9(4):311-7. PubMed PMID: 19666434.  
  11. Koçyildirim E, Yörükoğlu Y, Ekici E, Ikizler C. High-dose octreotide treatment for persistent pleural effusion after the extracardiac Fontan procedure. Anadolu Kardiyol Derg. 2008 Feb;8(1):75-6. PubMed PMID: 18258543.  
  12. Koçyildirim E, Kanani M, Bonhoeffer P, Elliott MJ. Amplatzer device embolization: hazards of multiple attempts at catheter retrieval. Anadolu Kardiyol Derg. 2007 Sep;7(3):329-30. PubMed PMID: 17785231.   
  13. Kocyildirim E, Franck LS, Elliott MJ. Intra-operative imaging in paediatric cardiac surgery: the reactions of parents who requested and watched a video of the surgery performed on their child. Cardiol Young. 2007 Aug;17(4):407-13. Epub  2007 Jun 25. PubMed PMID: 17588282.   
  14. Kostolny M, Kocyildirim E, de Leval MR, Anderson RH. Anomalous origin of the  right pulmonary artery from the ascending aorta with fibrous continuity to the pulmonary trunk. Ann Thorac Surg. 2005 Nov;80(5):1917-8. PubMed PMID: 16242486.   
  15. Pittaccio S, Migliavacca F, Dubini G, Koçyildirim E, de Leval MR. On the use  of computational models for the quantitative assessment of surgery in congenital  heart disease. Anadolu Kardiyol Derg. 2005 Sep;5(3):202-9. Review. PubMed PMID: 16140652.   
  16. Ricci M, Cohen GA, Kocyildirim E, Khambadkone S, Elliott MJ. Transposition of the great arteries and quadricuspid pulmonary valve: an unusual combination. Ann  Thorac Surg. 2005 Apr;79(4):1428-30. PubMed PMID: 15797105.   
  17. Kocyildirim E, Kanani M, Roebuck D, Wallis C, McLaren C, Noctor C, Pigott N,  Mok Q, Hartley B, Dunne C, Uppal S, Elliott MJ. Long-segment tracheal stenosis: slide tracheoplasty and a multidisciplinary approach improve outcomes and reduce  costs. J Thorac Cardiovasc Surg. 2004 Dec;128(6):876-82. PubMed PMID: 15573072.   
  18. Kanani M, Kocyildirim E, Cohen G, Bentham K, Elliott MJ. Method and value of  digital recording of operations for congenital heart disease. Ann Thorac Surg. 2004 Dec;78(6):2146-9; discussion 2149. PubMed PMID: 15561053.